First Define Fate

Both animals and humans act by instincts but humans like to think they are better than animals with “free will.” Humans invent reason and then apply it to their actions and this really makes them feel free. But even if we seem to have more choices than other animals our choices are within a
determinism.

Instincts do not preclude the human mind or brain, the mind only thinks it is free and beyond the  instincts. Sometimes our knowledge gets in the way of wisdom. Reason needs to bring itself in balance with determinism and freedom so that reason can be of help in better understanding ourselves and our fate.

Sociobiology has supplied the best available knowledge on free will and determinism, finding that we (and our cultures) live on a biologically determined leash that allows us some freedom to wander, but we are eventually pulled back to our determined human nature, which decides what we can and cannot create successfully, with success being measured by whether we and our group, and our genes, survive or not. Our free choices are defined within this sociobiological parameter... I think there is also a sacred dimension to this determinism which I discuss below.

Nietzsche's presocratic virtue of “accepting our fate” needs to be seen from this sociobiology perspective, which can then help us define fate. The more we know who we are the better we can define our fate.

Religion and the sacred enter this discussion regarding our fate when we broaden the freedom/determinism subject to theological materialism. I believe that material life is inwardly determined to evolve to Godhood in the cosmos, but this determinism is shaped back and forth and up and down outwardly by natural evolution. We have some help or direction in that there is a Spirit-Will within material life, still unseen by science, which activates life to evolve to Godhood.

To accept our fate means to bring ourselves, and our definitions of virtue, in balance with evolving to Godhood. The old virtues of temperance, prudence, courage, justice, and faith, hope and love, need to be balanced with our sacred evolution to Godhood. This we seek to do in the Twofold Path.