“But for this religious sanction and warrant of our senses and our reason, whence should we obtain our right to trust in existence.” (Nietzsche, “The Will To Power”)
Nietzsche meant the above quote sarcastically, cynically, but I take it seriously and uncynically. Theological materialism gives us not Nietzsche's superman, it gives us Godhood as the zenith of the evolved superman. This transvalues Nietzsche's tranvaluations back to religion again, which he rejected---although it was mostly Christianity that he disliked so much---he liked religious paganism.
We can keep the instincts---which religion has had big problems with---when Godhood is defined as the zenith of the evolved instincts. Traditional religion saw a preliminary God in the Inward Path to the Father Within, which can be retained but transformed in the Outward Path of material and supermaterial evolution to real Godhood.
As the goal of the unconscious Super-Id, or the goal of the instincts, Godhood is not only the highest consciousness having reached its goal of activating life to evolve to Godhood. Godhood is the unconscious become conscious in this sense, never separate from materialism or supermaterialism.
What do we desire? Happiness? (Aristotle's choice) Power? (Nietzsche's choice). These things are desired but the essential sacred desire is the Spirit-Will-To-Godhood---this activates life to evolve to the zenith of evolution, while being shaped by outside evolution. The placement, the hierarchy of these values is important; happiness and power attached to cultural ends are less profound than when these things are attached to our evolution to Godhood. It is not immoral to desire happiness or power, as the Inward Path necessarily teaches to how to see the God Within, it is just less important than the goal of evolving in the Outward Path to real Godhood.
Traditional religion has attempted to block and divert our instincts toward the God Within with varying degrees of success. What I have called the Super-Id of the instincts, defined here as the Spirit-Will-To-Godhood, is not the wild-beast-desiring-mainly-immoral power that Nietzsche thought it was, and it needs to be unblocked---it is difficult enough to reach higher evolution due to the shaping environmental vagaries of natural evolution---we need to help sacred evolution along.